International Board of Certified Lactation Consultant (IBCLC) Practice Exam

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Which herbal galactagogue may cause hepatotoxicity in some instances?

Chamomile
Comfrey
Ginger
Thistle

The correct answer is: Comfrey

Comfrey is recognized as an herbal galactagogue that may pose risks of hepatotoxicity. This herb contains pyrrolizidine alkaloids, which have been linked to severe liver damage when ingested over prolonged periods or in high doses. Due to its potential to cause toxicity, especially with chronic use, it is not recommended for lactating individuals seeking herbal support for milk production. In contrast, chamomile, ginger, and thistle are generally considered safer options. Chamomile is often used for its calming properties and has not been linked to liver toxicity. Ginger, known for its anti-inflammatory properties, is typically safe and well-tolerated, with no significant reports indicating hepatotoxic effects. Thistle, specifically milk thistle, is utilized for its liver-protective benefits and is also regarded as safe for lactation without significant risks of causing liver damage. Thus, while other herbs may offer lactation support, comfrey stands out due to its association with potential hepatotoxic risks.