International Board of Certified Lactation Consultant (IBCLC) Practice Exam

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When are levels of secretory IgA in human milk the highest?

In the first 24 hours after birth
In the first week after birth
In the first month after birth
In the first year after birth

The correct answer is: In the first 24 hours after birth

Levels of secretory IgA in human milk are highest in the first 24 hours after birth. This is significant because secretory IgA plays a crucial role in the newborn's immune system, offering protection against infections. The early colostrum produced in the first days after delivery is rich in immunoglobulins, particularly secretory IgA, which helps to provide passive immunity to the infant. During this time, the infant's own immune system is still developing, making it critical for them to receive these antibodies from their mother's milk. Over time, the concentration of secretory IgA in milk decreases as the milk transitions from colostrum to mature milk, which is why the first 24 hours are especially important for the infant's protection and health. This understanding highlights the importance of breastfeeding soon after birth for both the nutritional and immunological benefits it provides to the newborn.