International Board of Certified Lactation Consultant (IBCLC) Practice Exam

What is HAMLET in the context of human milk?

1. A human milk protein that enhances lactation

2. A human milk protein-lipid complex that kills tumors

3. A historical reference to milk consumption

4. A treatment for mastitis

The correct answer is: A human milk protein-lipid complex that kills tumors

HAMLET refers to a specific complex of proteins and lipids found in human breast milk that has been shown to exhibit tumoricidal properties. This protein-lipid complex is derived from alpha-lactalbumin, which is present in human milk. Research has indicated that HAMLET has the ability to induce apoptosis, or programmed cell death, in a range of tumor cells while sparing healthy cells. This discovery highlights the potential health benefits of human milk beyond basic nutrition, suggesting that components in breast milk may play a role in cancer prevention and treatment. The other choices do not accurately describe HAMLET's function or relevance within the context of human milk. While enhancing lactation and treating mastitis are important topics related to breastfeeding, they do not pertain to the specific attributes or scientific findings related to HAMLET and its impact on tumor cells. Similarly, historical references to milk consumption do not capture the biological significance that HAMLET has been found to possess in contemporary research.